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It must be combined with a daily topical application with one or more of the following ingredients to increase skin cell turnover: Glycolic acid (naturally derived from sugar cane) Bromelain (exfoliating enzyme found in Pineapples) Retinoids (Vitamin A derivatives) Salicylic acid (naturally derived from willow bark tree) Urea Lactic Acid If you suffer from extremely dry skin, choose body moisturisers which are high in Urea and Lactic Acid (a minimum concentration of 10% is best)